Vincristine cancer and curative effect of about 10 times higher than that of vinblastine, can be used in the treatment of acute lymphocytic leukemia, curative effect is better, for other acute leukemia, Hodgkin's disease, lymphatic sarcoma, the reticular cell sarcoma and breast cancer also has curative effect. A alkaloid found in Vincamajor in Vincamajor with vinblastine, panolulol and panellotine. It has the effect of stopping cell division (mitosis) in the medium term, which is similar to that of coldsin, but it is more powerful than the colchicine. It can bind to the microtubule and inhibit its biological activity, but the binding site is different. In addition, it also plays a role in protein such as actin and 10 nano-filaments, which are different from colchicine. It is used as an anticancer agent in clinical medicine, especially for hematopoietic organs. Vincrib sulfate can be used to treat Hodgkin's disease and chorionic epithelial carcinoma. For lymphatic sarcoma, the reticular cell sarcoma, acute leukemia (VP, VDLP scheme of "V" for vincristine, D for soft erythromycin, "L" for winter amidase door, "P" for prednisone), breast cancer, renal tumor, ovarian and testicular cancer, neuroblastoma, and malignant melanoma also have certain curative effect. (anti-tumor drug manual)

Our advantage

1. Free sample and unconditional assume respons
2. 100% natural porduct, without any synthetize ingredient
3. Manufacturer direct supply, provide OEM, R&D service
4. ISO/HACCP/KOSHER/GMP/FDA
5. Leading plant extract manufacturer in China
6. Our products are full inspection, all products have passed rigorous testing.
7. quality guarantee.
8. best quality materials
9. equipment imported from Germany,
10. production process is leading.
11. Our factories are dust-free.
12. Fast delivery
13. Able to meet the customer's orders
14. Our prices can make you beat your competitor in the market

Service we can provide

• Mixed container, we can mix different items in one container.
• Quality control, before shipment, free sample for test.
• Prompt shipment with professional documents
• Packing as your request, with photo before shipment
• High  quality and competitive price

Chinese name: vincristine

Molecular formula: C46H56N4O10

Molecular weight: 824.96

Product use: natural plant antitumor medicine for acute leukemia and malignant lymphoma, small cell lung cancer and breast cancer.

Pharmacological action:

Vincristine is an effective component in the extraction of periwinkle of oleander. The mice Ridgeway osteosarcoma, Mecca lymphatic sarcoma, x-5563 myeloma were also useful. Vincristine has a clear anticancer effect on the cultured human liver cell line (smmc-7721), which makes most cancer cells round when the concentration of vincristine is 100ng/ml and 50ng/ml. The envelope thickens and falls off into a suspended state. When the concentration is 100ng/ml and 50ng/ml, most of the tumor cells can be rounded, the cell membrane thickens, and it falls off and is suspended. Vincristine applied concentration of 100 ng/ml to cell to the next day and 50 ng/ml in 6 days, cell proliferation inhibition rate was obviously inhibition rate of 50%, attach vincristine concentration of 100 ng/ml in the role, 8 days after proliferation inhibition rate of 99.64% at the same time with the increase of concentration of VCR, inhibition rate increased to 75.21% protein content > 25 ng/ml, the killing rate of cancer cells as well as increased. Changchun new alkali has a strong inhibitory effect on human retinoblastoma cell line hox-rb44. Half of the inhibitory concentration IC50 is 0.31 ug/ml and changchun new alkali concentration reaches 0.01 ug/ml, which can significantly induce the apoptosis of K562 cells.

Therapeutic effect:

1. Acute leukemia, especially acute leukemia in children, has a significant effect on acute lymphocytic leukemia. Malignant lymphoma. 3. Germ cell tumor. 4. Small cell lung cancer, juve sarcoma, renal cell tumor, neuroblastoma. Breast cancer, chronic lymphocytic leukemia, gastrointestinal carcinoma, melanoma and multiple myeloma.

Drug action:

Vincristine is widely used in cancer chemotherapy regimens, but as a result of chemotherapy exists serious bone marrow suppression, gastrointestinal reactions and liver and kidney damage, so it need to be taken with synchronous selenium supplements, such as the agent of malt selenium selenium weikang chewed piece, use the function of selenium auxiliary control condition, repair the stomach of the body function, and improve immunity, can stimulate the bone marrow at the same time, the recovery of bone marrow hematopoietic function, also can enhance the susceptibility of cells to the chemical drug toxicity, reduce side effects, enhance the effect of chemotherapy.