Ergosterol, alias ergosterol, a white or colorless light or white crystalline powder. Ergosterol not only has a unique physiological function, but also is widely used in drug development. Ergosterol as an important component of fungal cell membrane, stable structure, strong specificity, for the determination of biomass, it is much more typical than glucosamine, so can be measured by testing the content of ergosterol fungal biomass. At present, the source of ergosterol is mainly synthesized from microbial fermentation. In recent years, scholars have also extracted from some mycelium.

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Chinese name: ergosterol

Chinese nickname: ergosterol; Ergosterol hydrate; (22E, 24R) - ergostane - 5, 7, 22 - triene-3 beta alcohol; (3 beta) - wheat horn - 5, 7, 22 - trienoglycerin - 3-alcohol; 3 beta - hydroxyl - (22E, 24R) - ergostane - 5, 722 - triene; Erythromycin C; 24 beta-methyl cholesterol - 5, 7-ene - 3 beta-alkyl

Molecular formula: C28H44O

Molecular weight: 396.65

Physicochemical properties:

Colorless needle or flake crystal. Dissolved in ethanol, ether, benzene and trichloromethane, insoluble in water. In the solvent of chloroform, ether or cyclohexane, it is added to the flask of quartz glass, which is used to prepare vitamin D.

Application:

Ergosterol is an important part of the microbial cell membrane, to ensure that the cell vitality, liquid membrane, membrane combined with enzyme activity, membrane integrity and cell material transportation plays an important role.

With good fluidity, yeast cell membrane has high resistance to frost.

The most commonly used antifungal drugs are for the ergosterol biosynthesis in the design of the key enzymes necessary inhibitor, combined with key enzyme, it is through a competitive inhibition of ergosterol synthetic, the fungal cell membrane is damaged, thus inhibiting the growth of fungi.

Ergosterol can enhance the ability of the body to fight disease, it is the important fat soluble vitamin D2 source, has the obvious anti-bacterial, anti-tumor effect. And it can be added to feed additives as feed additives, increasing the rate of egg production and incubation rates of livestock and poultry. Ergosterol can also be used as an important pharmaceutical chemical for the production of sterol such as cortisone and hormone progesterone