Scientific name: Glycyrriza Uralensis Fisch. G.

Alias: medgrass, migan, migam, old, pink grass, sweet grass, sweet root, good grass

Category: tonic

English name: Licorice Roots Northwest Origin

Latin name: Radix Glycyrrhizae

Plant name: licorice

Properties: yellow to tan powder

[identify]

(1) the cross section of this product: the cork layer is a series of brown cells. The cortex is narrower. The phloem ray is wide and curved and often cracks; Fibrous polymorphic bundles, not lignylation or microlignylation, surrounding thin-walled cells often containing calcium oxalate crystals; The screening group is often deformed by compression. There is an obvious layer of cambium. The xylem is 3-5 column cells; The catheter is more, the diameter is about 160 mu m; The wood fibers are bunched and the surrounding thin-walled cells also contain calcium oxalate. The root has no pulp; The root has a pulp. Powder light brown and yellow. The fibers are bundles of fibers, 8 ~ 14 mu m in diameter, and the wall is thick and micro wood, and the surrounding thin-walled cells contain calcium oxalate, forming crystalline fibers. See the calcium oxalate. The bordered perforated catheter is large and rare reticulated duct. Cork cells red brown, polygonal, microlignylation.

(2) apply the powder 1 g, plus ether 40 ml, heating reflux for 1 hour, filtration, liquid to add 30 ml of methanol, heating reflux for 1 hour, filtration, the filtrate zhenggan residue 40 ml water to dissolve, with n-butyl alcohol extract 3 times, every time 20 ml, merger, n-butyl alcohol liquid water washing three times, zhenggan residue add methanol 5 ml to dissolve, as the test solution. The other herbal medicines, 1g, were compared with the legal system. The ammonium glycyrrhizin was taken as the control product, and the methanol was prepared with a solution of 2mg per 1ml. According to the thin layer chromatography (appendix Ⅵ B) test, from the above three kinds of solution 1 ~ 2 mu l, each point in the same with 1% sodium hydroxide solution preparation of silica G thin layer plate, with ethyl acetate - formic acid, glacial acetic acid and water (15:1:1:2) as an agent, and taken out, dry spray with 10% ethanol solution of sulfuric acid in the 105 ℃ heating to the spot color is clear, can be examined under a uv lamp (365 nm). In the chromatogram, the fluorescence spots of the same color were displayed in the corresponding position of the control materials. In the corresponding position of the corresponding chromatogram, the same orange fluorescence spot.

[determination of content]

According to high performance liquid chromatography (appendix Ⅵ D).

The chromatographic conditions and the applicability of the system were filled with octadecyl silane bonding silica gel. Methanol - 0.2 mol/L acetate solution - glacial acetic acid (67:33:1) is the flow phase; The detection wavelength is 250nm. The theoretical plate number is not less than 2000 according to the mono-ammonium salt peak of glycyrrhizin.

The preparation of the reference substance solution Take about 10 mg ammonium glycyrrhetate single reference substance, precision said, 50 ml volumetric flask, dissolved in mobile phase and diluting to scale, shake well, for a quick (each 1 ml contains ammonium glycyrrhetate single reference substance 0.2 mg, reduced glycyrrhizic acid 0.1959 mg).

Powder in the preparation of test sample solution for this product is about 0.3 g, precision said, 50 ml volumetric flask, add flow meet 45 ml, ultrasonic processing (power 250 w, frequency of 20 KHZ) 30 minutes, remove and cool off, with mobile phase to scale, shake well, filtration, quick.

The determination of 10 mu l of the solution of the control product and the solution of the sample was obtained, and the liquid chromatograph was injected into the liquid chromatography.

This product contains glycyrrhizic acid (C42H62O16) not less than 2.0%.

Efficacy:

Licorice is a plant with great medicinal value, which is used by Chinese and western medicine. Western medicine has been using liquorice as an anti-phlegm, antitussive and sweet additives from gusila. In ancient Chinese materia medica "cold-induced febride, licorice is described for strong bones and muscles, increase strength and drug treatment of trauma, and put it as a top grade, says the king of the grass is most all the medicine, the few who don't have to.

In traditional Chinese medicine, licorice is classified as heart, lung, spleen and stomach. It has the effect of nourishing the spleen, invigorating the spleen, clearing and detoxifying, removing phlegm, relieving cough, relieving pain and relieving pain. It is used for the weakness of the spleen and stomach, the fatigue and fatigue, the shortness of the heart palpitation, the cough sputum, the acute pain in the abdomen, the body of the limb, the carbuncle swelling and the inflammation, the drug toxicity, the intensity of the drug. The dosage is 1.5-9mg.

Studies show that licorice has inhibition of monoamine oxidase and inhibit aldose reductase cause diabetes, spasmolysis analgesia, prevention and treatment of viral hepatitis, the treatment of senile osteoporosis, leishmania resistance, cancer prevention and resistance to HIV/AIDS (AIDS) viruses, and so on.

Its effect is reflected in whitening, sunblock two respects

Licorice extract whitening effect is mainly by inhibiting tyrosinase and dopa pigment interconvert enzyme (TRP - 2) activity, 2 hydroxy indole block 5, 6 - (DHl) polymerization, in order to prevent the formation of melanin, so as to achieve the effect of whitening skin.

In licorice extract, the components of sunscreen are generally flavonoids. Due to the conjugation of the molecular structure of licorice flavonoids, both uv and visible light show strong absorption. The molecules that absorb the high energy ultraviolet ray migrate from the ground state to the activation state, and then from the activation state to the ground state, releasing harmless and low-energy rays. Compared with synthetic sunscreen, licorice extract is used as a sunscreen and does not need to add antioxidants to the formula. It does not stimulate the skin, and it can absorb better.

【 function main treatment 】 : fill the spleen yiqi, clear heat detoxification, dispel phlegmy cough, relieve the pain, mediate the medicine. It is used for the weakness of the spleen and stomach, the fatigue and fatigue, the shortness of the heart palpitations, the coughing sputum, the acute pain in the abdomen, the limbs, the swelling of the carbuncle, the drug toxicity, the intensity.

[usage dosage] : internal: decoction, 3 ~ 9g (high dose 30 ~ 60g). External use: proper amount, decocting and washing; Or apply it.

Taboo:

Should not be used with the Peking euphorbia, lilac, gansui and seaweed.

Properties: antioxidant and anti-carcinogenic effects

Pharmacological action: anti-tumor action, anti-viral action, anti - inflammatory and anti-immune function, anti-ulcer action, cough and asthma, and liver protection